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Thank you Joss, I appreciate you taking the time to respond.
Moving on from this to installing the x-payments-connector-for-X-Cart-4.0.x-4.2.x on Xcart v4.1.10, I get the following text at the top of the page in the admin and the store front end, when applying the patch_4_1_12.diff

define('XC_TIME', time());  define('X_PAYMENT_TRANS_ALREADY_CAPTURED', 1); define('X_PAYMENT_TRANS_ALREADY_VOIDED', 2); define('X_PAYMENT_TRANS_ALREADY_REFUNDED', 4); define('X_PAYMENT_TRANS_ALREADY_ACCEPTED', 8); define('X_PAYMENT_TRANS_ALREADY_DECLINED', 16);  define('PAYMENT_NEW_STATUS', 1); define('PAYMENT_AUTH_STATUS', 2); define('PAYMENT_DECLINED_STATUS', 3); define('PAYMENT_CHARGED_STATUS', 4);  define('X_USE_PAYPAL_FLOW', true);      

Any idea what would cause this?

Thanks