[Victor D]

Yes, you just had to decrease the horizontal paddings values a bit.
for the rules below you should change the value if there is any.

Do not move the breadcrumbs with 'br' tag
just add some margin above it like this:
#location{
margin-top:15px;
}

also your .tabs are have absolute position for speedbar, that's why it messes with breadcrumbs so change from absolute to relative:
.tabs {position:relative;width:100%}

(the width was set to 80% so the tabs were not across the whole center column area )

The third line of your header is empty but is still has a height of 39px. So you should also change height to 0 for links to work properly
#header .line3{
height:0px
}